Dr. Corina Bondi Awarded New UPP/UPMC Academic Foundation Grant

 

Corina Bondi, Ph.D., Assistant Professor in Physical Medicine and Rehabilitation and at the Safar Center for Resuscitation Research, was awarded a highly competitive, one-year $50,000 Research Grant via a new funding mechanism through the University of Pittsburgh Physicians (UPP)/UPMC Academic Foundation. Dr. Bondi’s project is entitled “Interaction of chronic unpredictable stress and environmental enrichment on cognitive and depressive-like behaviors following traumatic brain injury”. For traumatic brain injury (TBI) survivors, cognitive dysfunction and depressive-like symptomatology may be augmented when persistent stress is present during the chronic phase of recovery. Therefore, this study aims to assess clinically-relevant cognitive-behavioral and anxiety-like dimensions sensitive to both TBI and chronic stress in rats, evaluate potential beneficial effects of environmental enrichment, a preclinical model of neurorehabilitation, as well as begin to address mechanistic questions regarding altered brain neurotransmission responsible for such behavioral deficits.