2017 Publications

Articles are listed in the order they are e-published.

November

Rehabilitative Success After Brain Trauma by Augmenting a Subtherapeutic Dose of Environmental Enrichment with Galantamine. de la Tremblaye PB, Wellcome JL, Wells de Witt B, Cheng JP, Skidmore ER, Bondi CO, Kline AE. Neurorehabil Neural Repair. 2017 Nov. [Epub Ahead of Print.]

Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass. Kim-Campbell N, Gretchen C, Callaway C, Felmet K, Kochanek PM, Maul T, Wearden P, Sharma M, Viegas M, Munoz R, Gladwin MT, Bayir H. Crit Care Med. 2017 Nov;45(11):e1123-e1130.

October

Lateral fluid percussion injury impairs hippocampal synaptic soluble N-ethylmaleimide sensitive factor attachment protein receptor complex formation. Carlson SW, Henchir J, CE Dixon, Front. Neurol, Oct 2017;8:532.

PEBP1 Wardens Ferroptosis by Enabling Lipoxygenase Generation of Lipid Death Signals.Wenzel SE, Tyurina YY, Zhao J, St Croix CM, Dar HH, Mao G, Tyurin VA, Anthonymuthu TS, Kapralov AA, Amoscato AA, Mikulska-Ruminska K, Shrivastava IH, Kenny EM, Yang Q, Rosenbaum JC, Sparvero LJ, Emlet DR, Wen X, Minami Y, Qu F, Watkins SC, Holman TR, VanDemark AP, Kellum JA, Bahar I, Bayır H, Kagan VE. Cell. 2017 Oct 19;171(3):628-641.e26. 

The pharmacogenomics of severe traumatic brain injury. Adams SM, Conley YP, Wagner AK, Jha RM, Clark RS, Poloyac SM, Kochanek PM, Empey PE. Pharmacogenomics. 2017 Oct 4.  [Epub ahead of print]

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease. Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascón S, Hatzios SK, Kagan VE, Noel K, Jiang X, Linkermann A, Murphy ME, Overholtzer M, Oyagi A, Pagnussat GC, Park J, Ran Q, Rosenfeld CS, Salnikow K, Tang D, Torti FM, Torti SV, Toyokuni S, Woerpel KA, Zhang DD. Cell. 2017 Oct 5;171(2):273-285. 

Breaking Into the Top Ten. Kochanek PM, Kissoon N. Pediatr Crit Care Med. 2017 Oct;18(10):913-914. 

The pharmacogenomics of severe traumatic brain injury. Adams SM, Conley YP, Wagner AK, Jha RM, Clark RS, Poloyac SM, Kochanek PM, Empey PE. Pharmacogenomics. 2017 Oct 4. 

September

TBI Rehabilomics Research: an Exemplar of a Biomarker-Based Approach to Precision Care for Populations with Disability. Wagner AK. Curr Neurol Neurosci Rep. 2017 Sep 19;17(11):84. 

ABCG2 c.421C>A Is Associated with Outcomes after Severe Traumatic Brain Injury.Adams SM, Conley YP, Ren D, Okonkwo DO, Puccio AM, Dixon CE, Clark RSB, Kochanek PM, Empey PE. J Neurotrauma. 2017 Sep 19. 

August

Big Data Not Yet Big Enough to Determine the Influence of Intracranial Pressure Monitoring on Outcome in Children With Severe Traumatic Brain Injury. Horvat CM, Kochanek PM. JAMA Pediatr. 2017 Aug 28. [Epub ahead of print] 

Cell-Free Plasma Hemoglobin and Male Gender Are Risk Factors for Acute Kidney Injury in Low Risk Children Undergoing Cardiopulmonary Bypass. Kim-Campbell N, Gretchen C, Callaway C, Felmet K, Kochanek PM, Maul T, Wearden P, Sharma M, Viegas M, Munoz R, Gladwin MT, Bayir H. Crit Care Med. 2017 Aug 31. [Epub ahead of print]

Cardiac Arrest Secondary to Lightning Strike: Case Report and Review of the Literature.Rotariu EL, Manole MD.Pediatr Emerg Care. 2017 Aug 1. [Epub ahead of print]

Oxidative lipidomics: applications in critical care.Anthonymuthu TS, Kim-Campbell N, Bayır H. Curr Opin Crit Care. 2017 Aug;23(4):251-256. 

Whole-Transcriptome Microarray Analysis Reveals Regulation of Rab4 by RBM5 in Neurons. Jackson TC, Kotermanski SE, Kochanek PM. Neuroscience. 2017 Aug 14. pii: S0306-4522(17)30572-9. [Epub ahead of print]

Therapeutic Hypothermia and Targeted Temperature Management With or Without the "Cold Stress" Response. Kochanek PM, Jackson TC. Ther Hypothermia Temp Manag. 2017 Aug 11 [Epub ahead of print] 

The far-reaching scope of neuroinflammation after traumatic brain injury. Simon DW, McGeachy MJ, Bayır H, Clark RSB, Loane DJ, Kochanek PM. Nat Rev Neurol. 2017 Aug 4. 

Minocycline Attenuates High Mobility Group Box 1 Translocation, Microglial Activation, and Thalamic Neurodegeneration after Traumatic Brain Injury in Postnatal Day 17 Rats.Simon DW, Aneja RK, Alexander H, Bell MJ, Bayır H, Kochanek PM, Clark RSB. J Neurotrauma. 2017 Aug 22.  [Epub ahead of print]

July

Difficult Intubation and Ventilation in an Infant With Retropharyngeal Abscess With Mediastinal Extension.Bruno MA, Drabek T, Manole MD.Pediatr Emerg Care. 2017 Jul 17.  [Epub ahead of print]

Primary Omental Torsion in a Pediatric Patient: Case Report and Review of the Literature. Madha ES, Kane TD, Manole MD. Pediatr Emerg Care. 2017 Jul 3. [Epub ahead of print]

A Case of Lenticulostriate Stroke Due to Minor Closed Head Injury in a 2-Year-Old Child: Role of Mineralizing Angiopathy.Fidan E, Cummings DD, Manole MD. Pediatr Emerg Care. 2017 Jul 3. [Epub ahead of print]

Comparable impediment of cognitive function in female and male rats subsequent to daily administration of haloperidol after traumatic brain injury. Free KE, Greene AM, Bondi CO, Lajud N, de la Tremblaye PBKline AE. Exp Neurol. 2017 Oct;296:62-68. Epub 2017 Jul 8.

Interfacility Transport Shock Index Is Associated With Decreased Survival in Children.Jennings RM, Kuch BA, Felmet KA, Orr RA, Carcillo JA, Fink EL. Pediatr Emerg Care. 2017 Jul 11.  [Epub ahead of print]

Mini Review of Controlled Cortical Impact: A Well-Suited Device for Concussion Research. Osier N, Dixon CE. Brain Sci. 2017 Jul 20;7(7). pii: E88.

Phase I randomized clinical trial of N-acetylcysteine in combination with an adjuvant probenecid for treatment of severe traumatic brain injury in children. Clark RSB, Empey PE, Bayır H, Rosario BL, Poloyac SM, Kochanek PM, Nolin TD, Au AK, Horvat CM, Wisniewski SR, Bell MJ.PLoS One. 2017 Jul 7;12(7):e0180280. 

Translational Stroke Research: Vision and Opportunities. Bosetti F, Koenig JI, Ayata C, Back SA, Becker K, Broderick JP, Carmichael ST, Cho S, Cipolla MJ, Corbett D, Corriveau RA, Cramer SC, Ferguson AR, Finklestein SP, Ford BD, Furie KL, Hemmen TM, Iadecola C, Jakeman LB, Janis S, Jauch EC, Johnston KC, Kochanek PM, Kohn H, Lo EH, Lyden PD, Mallard C, McCullough LD, McGavern LM, Meschia JF, Moy CS, Perez-Pinzon MA, Ramadan I, Savitz SI, Schwamm LH, Steinberg GK, Stenzel-Poore MP, Tymianski M, Warach S, Wechsler LR, Zhang JH, Koroshetz W. Stroke. 2017 Jul 27. [Epub ahead of print] 

ABCG2 c.421C>A is Associated with Outcomes Following Severe Traumatic Brain Injury. Adams SM, Conley YP, Ren D, Okonkwo DO, Puccio A, Dixon CE, Clark RS, Kochanek PM, Empey PE. J Neurotrauma. 2017 Jul 26. [Epub ahead of print]

Adding insight to injury: a new era in neurotrauma.Jha RM, Kochanek PM. Lancet Neurol. 2017 Aug;16(8):578-580. Epub 2017 Jul 11. 

June

Translating biomarkers from research to clinical use in pediatric neurocritical care: focus on traumatic brain injury and cardiac arrest.Prout AJ, Wolf MS, Fink EL. Curr Opin Pediatr. 2017 Jun;29(3):272-279.

Long-Term Deficits in Cortical Circuit Function after Asphyxial Cardiac Arrest and Resuscitation in Developing Rats.Middleton JW, Simons DJ, Simmons JW, Clark RSB, Kochanek PM, Shoykhet M.eNeuro. 2017 Jun 30;4(3). 

Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients. Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB. Neurocrit Care. 2017 Jun 13. [Epub ahead of print].

Modeling Fast-scan Cyclic Voltammetry Data from Electrically Stimulated Dopamine Neurotransmission Data Using QNsim1.0. Harun R, Grassi CM, Munoz MJ, Wagner AK. J Vis Exp. 2017 Jun 5;(124).

Translating biomarkers from research to clinical use in pediatric neurocritical care: focus on traumatic brain injury and cardiac arrest. Prout AJ, Wolf MS, Fink EL. Curr Opin Pediatr. 2017 Jun;29(3):272-279.

Brain-Specific Serum Biomarkers Predict Neurological Morbidity in Diagnostically Diverse Pediatric Intensive Care Unit Patients.Au AK, Bell MJ, Fink EL, Aneja RK, Kochanek PM, Clark RSB.Neurocrit Care. 2017 Jun 13.  [Epub ahead of print]

May

IGF-1 mediated neurogenesis involves a novel Rit1/Akt/Sox2 cascade. Mir S, Cai W, Carlson SW, Saatman KE, Andres DA, Scientific Reports, May 2017, 7:3283 

Brain injury results in lower levels of melatonin receptors subtypes MT1 and MT2. Osier ND, Pham L, Pugh BJ, Puccio A, Ren D, Conley YP, Alexander S, Dixon CE. Neurosci Lett. 2017 May 22;650:18-24.

In vivo transduction of neurons with TAT-UCH-L1 protects brain against controlled cortical impact injury. Liu H, Rose ME, Ma X, Culver S, Dixon CE, Graham SH. PLoS One. 2017 May 24;12(5):e0178049.

Guiding Pediatric Critical Care Medicine Toward a Bigger "Impression" in 2017 and Beyond. Kochanek PM, Kudchadkar SR, Kissoon N.Pediatr Crit Care Med. 2017 May;18(5):403-404.

Titrating the dose of oxygen after severe traumatic brain injury in the era of precision medicine. Kochanek PM, Bayir H. J Neurotrauma. 2017 May 24. [Epub ahead of print]

Dietary Supplementation With Nonfermentable Fiber Alters the Gut Microbiota and Confers Protection in Murine Models of Sepsis. Morowitz MJ, Di Caro V, Pang D, Cummings J, Firek B, Rogers MB, Ranganathan S, Clark RSB, Aneja RK. Crit Care Med. 2017 May;45(5):e516-e523.

April

Effects of DHA on Hippocampal Autophagy and Lysosome Function After Traumatic Brain Injury.Yin Y, Li E, Sun G, Yan HQ, Foley LM, Andrzejczuk LA, Attarwala IY, Hitchens TK, Kiselyov K, Dixon CE, Sun D. Mol Neurobiol. 2017 Apr 1. [Epub ahead of print]

Polynitroxylated Pegylated Hemoglobin-A Novel, Small Volume Therapeutic for Traumatic Brain Injury Resuscitation: Comparison to Whole Blood and Dose Response Evaluation. Brockman EC, Jackson TCDixon CE, Bayɪr H, Clark RS, Vagni V, Feldman K, Byrd C, Ma L, Hsia C, Kochanek PM. J Neurotrauma. 2017 Apr 1;34(7):1337-1350. 

Refining environmental enrichment to advance rehabilitation based research after experimental traumatic brain injury. Radabaugh HL, LaPorte MJ, Greene AM, Bondi CO, Lajud N, Kline AE. Exp Neurol. 2017 Apr 27;294:12-18. [Epub ahead of print]

International Survey of Critically Ill Children With Acute Neurologic Insults: The Prevalence of Acute Critical Neurological Disease in Children: A Global Epidemiological Assessment Study. Fink EL, Kochanek PM, Tasker RC, Beca J, Bell MJ, Clark RS, Hutchison J, Vavilala MS, Fabio A, Angus DC, Watson RS; Prevalence of Acute critical Neurological disease in children: A Global Epidemiological Assessment (PANGEA) Investigators. Pediatr Crit Care Med. 2017 Apr;18(4):330-342.

Delirium in Critically Ill Children: An International Point Prevalence Study. Traube C, Silver G, Reeder RW, Doyle H, Hegel E, Wolfe HA, Schneller C, Chung MG, Dervan LA, DiGennaro JL, Buttram SD, Kudchadkar SR, Madden K, Hartman ME, deAlmeida ML, Walson K, Ista E, Baarslag MA, Salonia R, Beca J, Long D, Kawai Y, Cheifetz IM, Gelvez J, Truemper EJ, Smith RL, Peters ME, O'Meara AM, Murphy S, Bokhary A, Greenwald BM, Bell MJ. Crit Care Med. 2017 Apr;45(4):584-590. 

Derivation and Validation of a Serum Biomarker Panel to Identify Infants With Acute Intracranial Hemorrhage. Berger RP, Pak BJ, Kolesnikova MD, Fromkin J, Saladino R, Herman BE, Pierce MC, Englert D, Smith PT, Kochanek PM. JAMA Pediatr. 2017 Apr 10:e170429.

Ventricular Fibrillation Cardiac Arrest Produces a Chronic Striatal Hyperdopaminergic State that is Worsened by Methylphenidate Treatment. Nora GJ, Harun R, Fine DF, Hutchison D, Grobart AC, Stezoski JP, Munoz M, Kochanek PM, Leak RK, Drabek T, Wagner AK . J Neurochem. 2017 Apr 26.

Abusive Head Trauma and Mortality-An Analysis From an International Comparative Effectiveness Study of Children With Severe Traumatic Brain Injury. Miller Ferguson N, Sarnaik A, Miles D, Shafi N, Peters MJ, Truemper E, Vavilala MS, Bell MJ, Wisniewski SR, Luther JF, Hartman AL, Kochanek PM; Investigators of the Approaches and Decisions in Acute Pediatric Traumatic Brain Injury (ADAPT) Trial. Crit Care Med. 2017 Apr 20.

ABCB1 genotype is associated with fentanyl requirements in critically Ill children. Horvat CM, Au AK, Conley YL, Kochanek PM, Li L, Poloyac SL, Empey PE, Clark RS. Pediatr Res. 2017 Apr 7. 

A "Metamorphosis" in Our Approach to Treatment Is Not Likely to Result From a Meta-Analysis of the Use of Therapeutic Hypothermia in Severe Traumatic Brain Injury. Wallisch JS, Kochanek PM. Crit Care Med. 2017 Apr;45(4):744-745.

March

Lithium increases hippocampal SNARE protein abundance after traumatic brain injury. Carlson SW, Yan HQ, CE Dixon. Exp Neurol, March 2017, 289:55-63. 

Hemodialysis Clinic Social Networks, Sex Differences, and Renal Transplantation.Gillespie A, Fink EL, Traino HM, Uversky A, Bass SB, Greener J, Hunt J, Browne T, Hammer H, Reese PP, Obradovic Z.Am J Transplant. 2017 Mar 18.  [Epub ahead of print]

Pediatric Multiple Organ Dysfunction in Resource Limited Settings. Fink EL, Kissoon N. Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S83-S85.

The far-reaching scope of neuroinflammation after traumatic brain injury. Simon DW, McGeachy MJ, Bayır H, Clark RS, Loane DJ, Kochanek PM. Nat Rev Neurol. 2017 Mar;13(3):171-191.

Biochemical signaling by remote ischemic conditioning of the arm versus thigh: Is one raise of the cuff enough? Dezfulian C, Taft M, Corey C, Hill G, Krehel N, Rittenberger JC, Guyette FX, Shiva S. Redox Biol. 2017 Mar 18;12:491-498.

Translating biomarkers from research to clinical use in pediatric neurocritical care: focus on traumatic brain injury and cardiac arrest. Prout AJ, Wolf MS, Fink EL. Curr Opin Pediatr. 2017 Mar 17.

Pediatric Multiple Organ Dysfunction in Resource Limited Settings. Fink EL, Kissoon N. Pediatr Crit Care Med. 2017 Mar;18(3_suppl Suppl 1):S83-S85.

Sulfonylurea Receptor-1: A Novel Biomarker for Cerebral Edema in Severe Traumatic Brain Injury. Jha RM, Puccio AM, Chou SH, Chang CH, Wallisch JS, Molyneaux BJ, Zusman BE, Shutter LA, Poloyac SM, Janesko-Feldman KL, Okonkwo DO, Kochanek PM. Crit Care Med. 2017 Mar;45(3):e255-e264

Physical and occupational therapy utilization in a pediatric intensive care unit. Cui LR, LaPorte M, Civitello M, Stanger M, Orringer M, Casey F 3rd, Kuch BA, Beers SR, Valenta CA, Kochanek PM, Houtrow AJ, Fink EL. J Crit Care. 2017 Mar 7;40:15-20. 

Psychometric evaluation of the pediatric and parent-proxy Patient-Reported Outcomes Measurement Information System and the Neurology and Traumatic Brain Injury Quality of Life measurement item banks in pediatric traumatic brain injury. Bertisch H, Rivara FP, Kisala PA, Wang J, Yeates KO, Durbin D, Zonfrillo MR, Bell MJ, Temkin N, Tulsky DS. Qual Life Res. 2017 Mar 7.

Pediatric cardiac arrest due to drowning and other respiratory etiologies: Neurobehavioral outcomes in initially comatose children. Slomine BS, Nadkarni VM, Christensen JR, Silverstein FS, Telford R, Topjian A, Koch JD, Sweney J, Fink EL, Mathur M, Holubkov R, Dean JM, Moler FW; Therapeutic Hypothermia after Pediatric Cardiac Arrest THAPCA Trial Investigators. Resuscitation. 2017 Mar 6. pii: S0300-9572(17)30104-1. 

Global assessment of oxidized free fatty acids in brain reveals an enzymatic predominance to oxidative signaling after trauma. Anthonymuthu TS, Kenny EM, Amoscato AA, Lewis J, Kochanek PM, Kagan VE, Bayır H. Biochim Biophys Acta. 2017 Mar 24.

Adenosine production by brain cells. Jackson EK, Kotermanski SE, Menshikova EV, Dubey RK, Jackson TC, Kochanek PM. J Neurochem. 2017 Mar 13. 

February

Contemporary animal models of cardiac arrest: A systematic review. Vognsen M, Fabian-Jessing BK, Secher N, Løfgren B, Dezfulian C, Andersen LW, Granfeldt A. Resuscitation. 2017 Apr;113:115-123. doi: 10.1016/j.resuscitation.2017.01.024. Epub 2017 Feb 15. 

Cerebrospinal Fluid NLRP3 is Increased After Severe Traumatic Brain Injury in Infants and Children. Wallisch JS, Simon DW, Bayır H, Bell MJ, Kochanek PM, Clark RS.Neurocrit Care. 2017 Feb 8.

α-Tocopherol transfer protein mediates protective hypercapnia in murine ventilator-induced lung injury. Otulakowski G, Engelberts D, Arima H, Hirate H, Bayir H, Post M, Kavanagh BP. Thorax. 2017 Feb 3.

Acute Management of Refractory and Unstable Pediatric Supraventricular Tachycardia. Lewis J, Arora G, Tudorascu DL, Hickey RW, Saladino RA, Manole MD. J Pediatr. 2017 Feb;181:177-182.e2. 

Tripartite Stratification of the Glasgow Coma Scale in Children with Severe Traumatic Brain Injury and Mortality: An Analysis from a Multi-Center Comparative Effectiveness Study. Murphy S, Thomas NJ, Gertz SJ, Beca J, Luther JF, Bell MJ, Wisniewski SR, Hartman AL, Tasker RC. J Neurotrauma. 2017 Feb 27.

Examining Emergency Department Treatment Processes in Severe Pediatric Traumatic Brain Injury. Ajdari A, Boyle LN, Kannan N, Rowhani-Rahbar A, Wang J, Mink R, Ries B, Wainwright M, Groner JI, Bell MJ, Giza C, Zatzick DF, Ellenbogen RG, Mitchell PH, Rivara FP, Vavilala MS. J Health Qual. 2017 Feb 3. 

The Brain and Hypothermia-From Aristotle to Targeted Temperature Management. Kochanek PM, Jackson TC. Crit Care Med. 2017 Feb;45(2):305-310

January

Lipidomics Characterization of Biosynthetic and Remodeling Pathways of Cardiolipins in Genetically and Nutritionally Manipulated Yeast Cells. Tyurina YY, Lou W, Qu F, Tyurin VA, Mohammadyani D, Liu J, Hüttemann M, Frasso MA, Wipf P, Bayir H, Greenberg ML, Kagan VE. ACS Chem Biol. 2017 Jan 20;12(1):265-281.

 ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition. Doll S, Proneth B, Tyurina YY, Panzilius E, Kobayashi S, Ingold I, Irmler M, Beckers J, Aichler M, Walch A, Prokisch H, Trümbach D, Mao G, Qu F, Bayir H, Füllekrug J, Scheel CH, Wurst W, Schick JA, Kagan VE, Angeli JP, Conrad M. Nat Chem Biol. 2017 Jan;13(1):91-98. 

Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis. Kagan VE, Mao G, Qu F, Angeli JP, Doll S, Croix CS, Dar HH, Liu B, Tyurin VA, Ritov VB, Kapralov AA, Amoscato AA, Jiang J, Anthonymuthu T, Mohammadyani D, Yang Q, Proneth B, Klein-Seetharaman J, Watkins S, Bahar I, Greenberger J, Mallampalli RK, Stockwell BR, Tyurina YY, Conrad M, Bayır H. Nat Chem Biol. 2017 Jan;13(1):81-90. 

Known unknowns of cardiolipin signaling: The best is yet to come. Maguire JJ, Tyurina YY, Mohammadyani D, Kapralov AA, Anthonymuthu TS, Qu F, Amoscato AA, Sparvero LJ, Tyurin VA, Planas-Iglesias J, He RR, Klein-Seetharaman J, Bayır H, Kagan VE. Biochim Biophys Acta. 2017 Jan;1862(1):8-24. 

Elimination of the unnecessary: Intra- and extracellular signaling by anionic phospholipids. Kagan VE, Bayır H, Tyurina YY, Bolevich SB, Maguire JJ, Fadeel B, Balasubramanian K. Biochem Biophys Res Commun. 2017 Jan 15;482(3):482-490. 

Magic angle spinning 31P NMR spectroscopy reveals two essentially identical ionization states for the cardiolipin phosphates in phospholipid liposomes. Kooijman EE, Swim LA, Graber ZT, Tyurina YY, Bayır H, Kagan VE. Biochim Biophys Acta. 2017 Jan;1859(1):61-68. 

The benefits of youth are lost on the young cardiac arrest patient. Griffith B, Kochanek P, Dezfulian C. F1000Res. 2017 Jan 25;6:77.

Epidemiology of Comorbid Conditions Among Adults 50 Years and Older With Traumatic Brain Injury. Kumar RG, Juengst SB, Wang Z, Dams-OʼConnor K, Dikmen SS, OʼNeil-Pirozzi TM, Dahdah MN, Hammond FM, Felix ER, Arenth PM, Wagner AK. J Head Trauma Rehabil. 2017 Jan 5.

Probabilistic Matching Approach to Link Deidentified Data from a Trauma Registry and a Traumatic Brain Injury Model System Center. Kesinger MR, Kumar RG, Ritter AC, Sperry JL, Wagner AK. Am J Phys Med Rehabil. 2017 Jan;96(1):17-24.

Therapeutic Hypothermia after In-Hospital Cardiac Arrest in Children. Moler FW, Silverstein FS, Holubkov R, Slomine BS, Christensen JR, Nadkarni VM, Meert KL, Browning B, Pemberton VL, Page K, Gildea MR, Scholefield BR, Shankaran S, Hutchison JS, Berger JT, Ofori-Amanfo G, Newth CJ, Topjian A, Bennett KS, Koch JD, Pham N, Chanani NK, Pineda JA, Harrison R, Dalton HJ, Alten J, Schleien CL, Goodman DM, Zimmerman JJ, Bhalala US, Schwarz AJ, Porter MB, Shah S, Fink EL, McQuillen P, Wu T, Skellett S, Thomas NJ, Nowak JE, Baines PB, Pappachan J, Mathur M, Lloyd E, van der Jagt EW, Dobyns EL, Meyer MT, Sanders RC Jr, Clark AE, Dean JM; THAPCA Trial Investigators. N Engl J Med. 2017 Jan 26;376(4):318-329.